Rejuran
Rejuran represents a new generation of innovative treatments using polynucleotide (PN) amino acids to address a wide range of skin concerns, while also promoting overall skin health. These include signs of ageing, textural irregularities, fine lines and wrinkles. Polynucleotide injections utilise DNA fragments derived from wild salmon to stimulate the skin’s natural regeneration processes, resulting in healthier, more youthful looking skin.
Rejuran activates fibroblasts, which are the skin cells responsible for producing collagen and elastin. This stimulation enhances skin thickness, improves elasticity and promotes skin tightening. Increased collagen levels support skin hydration, which contributes to a more luminous, youthful and healthier appearance. The treatment works to slow the ageing process, improve hydration, minimise the appearance of pores, fine lines and wrinkles, enhance firmness and soften visible scarring and support a more even skin tone by helping to reduce pigmentation.
The active ingredient in Rejuran is concentrated polynucleotides extracted from salmon DNA. Polynucleotides contain high levels of nucleic acids and are naturally occurring compounds already present in human skin. Rejuran injections replenish these compounds to accelerate the skin’s natural healing, repair, hydration, and regenerative functions. This also helps reduce inflammation, improve pigmentation irregularities, and supports overall skin vitality.
Rejuran injections replenish these compounds to accelerate the skin’s natural healing, repair, hydration, and regenerative functions. This also helps reduce inflammation, improve pigmentation irregularities, and support overall skin vitality.
Benefits
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The polynucleotides in Rejuran stimulate collagen and elastin production, resulting in smoother, firmer, healthier and more hydrated skin. Fine lines and wrinkles are reduced, and visible results are typically seen for up to 12 months.
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Skin tone and texture are visibly improved, pigmentation irregularities may be reduced, and pores and imperfections appear diminished. Skin appears softer, more supple, and better hydrated.
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Rejuran works by promoting the skin’s own repair and maintenance processes. It is effective in improving fine lines, wrinkles, skin tone, elasticity, pigmentation irregularities, enlarged pores, and both acne and surgical scars.
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Rejuran is a minimally invasive treatment with little to no downtime. Small raised bumps may be present at the injection sites immediately post-treatment, typically, they resolve within 24–48 hours. Discomfort is generally mild and well tolerated. A topical numbing cream may be applied 30 minutes prior to enhance comfort. As the injection involves compounds naturally found in human tissue, side effects are rare and easily managed.
Treatments
Rejuran is available in several formulations, each tailored to specific concerns:
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A targeted treatment for the delicate skin around the eyes. It addresses fine lines, wrinkles, dark circles, and pigmentation-related concerns such as uneven tone or discoloration. It also helps improve crepiness.
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A full-face rejuvenation and hydration treatment. It’s also used to improve the elasticity of neck skin.
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Designed to reduce the appearance of acne, surgical and trauma related scarring.
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A comprehensive skin quality treatment that enhances hydration, refines texture and improves skin luminosity, while reinforcing the skin barrier. It is ideal for those seeking a brighter, healthier complexion with fewer fine lines and increased elasticity. It’s best used after a microneedling treatment to amplify the microneedling results. It accelerates skin renewal and supports collagen production for smoother, more resilient skin.
FAQs
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Rejuran is suitable for all skin types, tones, and ethnicities. Rejuran is used for both preventative care and for treating age-related skin concerns such as fine lines, dullness, dryness, sun damage, acne scarring, enlarged pores, uneven skin tone, and pigmentation irregularities, as well as post-surgical scarring. It’s also suitable for younger patients (20s to 30s) who are looking to maintain skin health.
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Polynucleotides are naturally occurring and present in human DNA. The compound is low risk. Side effects are rare and typically mild. Small bumps at injection sites, similar in appearance to mosquito bites are common. They resolve within one to two days naturally. Mild swelling or bruising may occur and should dissipate within four to five days. Discomfort during treatment is usually minor and short-lived. Serious adverse reactions are extremely rare.
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Results are progressive. As Rejuran stimulates your body’s natural regenerative processes, changes gradually become noticeable. This typically occurs between two to four weeks after treatment, depending on individual factors such as age, overall health, and lifestyle.
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Results typically last up to 12 months. Duration depends on age, lifestyle, initial skin condition and the number of treatments completed. Improvements emerge gradually. You will notice improvement for several months. Unlike fillers or bio-remodellers, Rejuran delivers long-term benefits through natural collagen regeneration. Maintenance sessions can help prolong and optimise results.
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A course of 2 to 3 sessions, spaced 2 to 4 weeks apart, is usually recommended. Maintenance treatments every 6 to 12 months help to sustain results. The number of sessions depends on your individual skin condition and the desired outcome.
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A topical numbing cream is applied before treatment to maximise comfort. Most patients report only mild discomfort and minor or no post treatment soreness.
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Most clients can resume daily activities the same day, albeit with reduced social engagement. Redness and small bumps may be present for 24 to 72 hours post-treatment. It’s advisable not to schedule important social events immediately after treatment.
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Yes. Rejuran complements other cosmetic procedures and your skincare routine. Its anti-inflammatory and regenerative properties help support faster recovery and improve treatment outcomes.
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Rejuran can be applied to any area requiring skin rejuvenation. Common treatment areas include the face, under eyes, neck, décolletage, hands and scars. It is especially effective for enlarged pores, uneven tone, pigmentation irregularities, fine lines, and skin affected by acne or surgical scarring.
Risks, Contraindications & Aftercare
Contraindications
Rejuran should not be used if you:
Are pregnant or breastfeeding
Have an active skin infection or inflammation in or around the treatment area
Have an autoimmune condition or a disorder affecting the immune system
Post Care
Following treatment, we recommend:
Avoiding excessive sun exposure and applying broad-spectrum sunscreen SPF 30+ daily.
Refraining from strenuous exercise or physical activity for 48 hours.
Avoiding active skincare products such as retinol, ascorbic acid (Vitamin C), and AHA/BHA exfoliants for 48 hours to minimise irritation.
Common Side Effects
Redness, swelling, or mild irritation at injection sites
Bruising or pinpoint bleeding where injections were administered
Tenderness or mild pain for a few days
Temporary skin tightness or itching
Less Common Risks
Small lumps or nodules under the skin (usually resolve on their own)
Hyperpigmentation (temporary darkening of the skin in treated areas)
Allergic reaction (rare, since Rejuran is generally biocompatible)
Rare but Serious Risks
Infection at the injection site
Persistent swelling or asymmetry
Vascular complications if injected incorrectly (extremely rare)
Other Considerations
Results are gradual and often require a series of treatments
Rejuran does not replace a healthy lifestyle or medical skincare for underlying conditions
Proper injection technique by a qualified practitioner minimises risks.